Catholic Relief Services (CRS) in collaboration with partners in Ghana, Zambia, Kenya and Malawi is implementing a three-year SCORE ECD III project with support from Conrad and Hilton Foundation, through Catholic Sister organizations towards achieving the goal children 0-3 years old in the target areas live in nurturing environments by 2024. Phase III of the project is supporting the sustainability and leadership of 5 National Associations and 32 Congregations of Catholic Sisters in the four countries. The project is strengthening sisters’ organizations, adapting and refining the SCORE model by scaling up a targeted maternal mental health component, incorporating household economic strengthening, SMART Couples interventions, and introducing a quality improvement component in Sister-managed health facilities. The project theory of change is that if Catholic Sisters and their organizations continue to expand and improve their technical and organizational capacities, then they will more effectively and sustainably provide services to caregivers of young children, leading to those caregivers being better able to provide nurturing care, which ultimately improves child development outcomes. At the same time, if Catholic Sisters and their organizations become more effective and sustainable, then they will be better placed to provide leadership and influence at the policy level, contributing to an enabling environment for children and families across the target countries to thrive.